Che-Yu Lee is a bioinformatics scientist with extensive experience in next-generation sequencing (NGS) data analysis, clinical assay development, and computational genomics. He currently serves as a Staff Bioinformatics Scientist at Guardant Health, where he develops and optimizes genomic and epigenomic pipelines for applications in cancer screening, minimal residual disease detection, and treatment response monitoring. He has strong expertise in algorithm development, statistical modeling, and machine learning, with a focus on improving variant detection accuracy, reducing false positives, and enabling robust analysis of both tissue and cfDNA data.

Che-Yu Lee 是一位生物資訊科學家，擁有豐富的次世代定序（NGS）數據分析、臨床檢測開發及計算基因體學經驗。目前任職於 Guardant Health 擔任資深生物資訊科學家，負責開發與優化基因體與表觀基因體分析流程，應用於癌症篩檢、微小殘留病灶（MRD）偵測及治療反應監測。他在演算法開發、統計建模與機器學習方面具有深厚專長，專注於提升變異檢測的準確性、降低偽陽性率，並強化組織切片與游離DNA（cfDNA）數據的分析能力。